Doctors Without Borders/Médecins Sans Frontières (MSF) is an international humanitarian medical aid organization working in more than 65 countries worldwide. Médecins Sans Frontières is neutral, impartial, independent, and not linked to any political party or governmental body. It provides emergency medical assistance to people in need, irrespective of their nationality, race or religion. In 1996, MSF received the Indira Gandhi Prize for Peace, Disarmament and Development and in 1999 MSF was awarded the Nobel Peace Prize. MSF has worked in India since 1999 and provides medical treatment to hundreds of thousands of Indian patients.
Project Summary :
One third of all HIV patients worldwide live in regions where leishmaniasis is endemic. Visceral leishmaniasis (VL) caused by the parasite L.donovani is endemic to Bihar, a populous state of 110 million people in East India, which carries an estimated 40% of the world’s VL burden. Although Bihar has a relatively low prevalence of HIV (between 0.22 - 0.33%), its high population density means that in absolute numbers an estimated 300,000 people in the state live with HIV/AIDS.
Moreover, Bihar is one of the few states in India where the rate of new HIV infections is increasing. This has major implications for VL co-infection: like other opportunistic infections in HIV patients, Leishmania amastigotes have evolved strategies to survive which are enhanced by HIV co-infection and accelerate progression of disease. This may help explain why the risk of developing VL is estimated to be between 100 and 2300 times higher in HIV-infected individuals than in those who are HIV-negative. Evidence on the prevalence of HIV-VL co-infection in India is scarce, although estimates range from 2-6%. HIV-VL co-infection therefore appears to be an emerging public health issue in India.
The evidence base regarding best treatment practices for co-infected patients worldwide is limited, due to a lack of randomized trials and to the fact that most available data comes from observational studies with relatively short follow-up periods, and often with high rates of loss to follow-up. Nevertheless, worse outcomes in almost every respect have consistently been reported in this patient group when compared to patients not known to be HIV-positive—for example, in terms of higher relapse rates, mortality, and VL drug toxicity and treatment failure.
All of the existing evidence regarding co-infected patients treated with AmBisome® in the Indian context has been generated from retrospective programmatic observational data by Medicins Sans Frontieres (MSF) and the Rajindra Memorial Research Institute (RMRI). The outcomes for these co-infected patients were substantially worse than for VL patients not known to be HIV-positive receiving the same VL treatment in the same setting, where the estimated all-cause mortality and relapse rates at 15 months for patients not known to be HIV positive were 2.8% and 1.2% respectively, compared to 18.1% and 16.1% at 12 months respectively for co-infected patients.
Considering the lack of quality evidence surrounding treatment for co-infected patients in the Indian context, MSF along with RMRI is conducting a study examining the effectiveness of 40mg/kg AmBisome® —as recommended by the WHO for VL-HIV co-infection but never tested in India or on L. donovani in the Indian subcontinent —and a lower dose combination of 30 mg/kg of AmBisome® and Miltefosine (100 mg daily for 14 days) be formally evaluated in order to provide the Indian policy makers with evidence to develop specific guidelines for the treatment of co-infected patients.
Position Code: MT034
Number of posts available: 1
Location: RMRIMS, Patna
Project: HIV/VL Co infection & Operational Research
Start Date: 1st March 2017
Email: email@example.com & firstname.lastname@example.org
Purpose of Post :
Provide outpatient and/or inpatient medical care to MSF beneficiaries according to MSF protocols, values, universal hygiene standards, as defined in the project objectives and operational research.
Functional and Hierarchical Lines
Hierarchically accountable to Field Coordinator and functionally accountable to the Medical Activities Manager-RMRI.
Main responsibilities and tasks
• Entry of routine project and trial data into system and to look for missing data /outliers and to assure the quality control of data that is entered in the system;
• Entry of medical stock movement in Isystock software from stock card;
• Extract the report and Data check-up from Isystock;
• Prepare the Medical stock accountability system in excel sheet if required;
• Regularly or when is necessary: analyse and report the outcomes of the Project;
• Able to preserve the total patient confidentiality;
• Follow the MSF internal policy;
• Participation in other coordinated activities with the rest of the MSF team;
• Follow the MSF data security guidelines;
• To support medical team in continually evaluating and improving the data collection and data analysis process;
• Maintain and ensure confidentiality of all collected and stored information.
• Create and enforce policies for effective data management.
• Formulate techniques for quality data collection to ensure adequacy, accuracy and legitimacy of data
• Support others in the daily use of data systems and ensure adherence to MSF standard
• Assist with reports and data extraction when needed
• Monitor and analyse information and data systems and evaluate their performance to discover ways of enhancing them
• Ensure digital databases and archives are protected from security breaches and data losses
• Troubleshoot data-related problems and authorize maintenance or modifications
• To maintain a flexible approach and responds to the needs of the project even if outside of this job description.
• To perform any other tasks as required by the Supervisor
• Preferably at least years of work experience in similar profile.
• Previous experience in research related work
• Previous experience of MSF, UN organization or other international NGOs
• Familiarity with modern database and information system technologies
• An analytical mindset with problem-solving skills
HR & Benefits
• Salary Package: 23, 507 INR gross/month.
• Benefit of 13th Month Salary.
• PF and Gratuity are applicable as per law.
• TOTAL LEAVES: 27 leaves + 12 public holidays per year.
• Wide Medical coverage (Employee + Direct Relatives), as per organization policy.
To apply please email your CV and covering letter with the subject Ref: Head DEO to email@example.com & firstname.lastname@example.org on or before 19th February 2017.
Job Email id: msfe-delhi-recruitment(at)barcelona.msf.org
• Excellent understanding of data administration and management functions (collection, analysis, distribution etc.)
• Proficient in MS Office (Excel, Access, Word etc.)
• Excellent communication and collaboration skills